Paul Santiago, MD
Disclosures: Consulting Fee-Cerapedics, Mizuho|Ownership Interest-Corelink|Royalty-Globus, Zimmer
Curriculum Vitae

Paul Santiago, MD

Curriculum Vitae

 

Paul Santiago, MD

Curriculum Vitae

 

               

Office Address                       Department of Neurological Surgery

              Washington University School of Medicine

              660 South Euclid Avenue, Campus Box 8057

              Saint Louis, MO  63110

              Phone (314) 747-6144

              Fax (314) 362-2107

 

Present Position              2016-present              Professor of Neurological and 

                            Orthopaedic Surgery          

                                                           Washington University School of Medicine

 

 

 Education                           1986-1990              Stanford University - B.Sc., with Honors (Biology)

 

              1990-1995              Yale Medical School - M.D.

 

              1995-1996              Intern, General Surgery

              University of Washington

 

              1996-2000              Resident, Neurological Surgery

                            University of Washington

 

2000-2001                    Specialist Registrar, Neurological Surgery

Atkinson Morley’s Hospital, London

 

             

 

              2001-2002              Chief Resident,  Neurological Surgery

                            University of Washington

 

              2002-2003          Spine Fellow, Neurological Surgery

                                                                        University of Chicago

 

Academic Positions              2016-present              Professor of Neurological and 

                            Orthopaedic Surgery          

                                                           Washington University School of Medicine

 

              2010-2016              Associate Professor of Neurological and 

                            Orthopaedic Surgery          

                                                           Washington University School of Medicine

 

                                             2003-2010              Assistant Professor of Neurological and

              Orthopaedic Surgery

              Washington University School of Medicine

 

Hospital Privileges              2003-present              Barnes Jewish Hospital, Saint Louis, MO

              St. Louis Children’s Hospital, Saint Louis, MO

              Barnes West County Hospital, St. Louis, MO

 

 

University and Hospital Appointments and Committees:

 

Coding and Outcomes Committee, Dept. of Neurological Surgery, Washington University in St. Louis. 2013-present. 

             

Medical Staff Performance Committee, Chair. Barnes Jewish Hospital. 2014-present. 

 

Midlevel Professional Program, Director. Dept. of Neurological Surgery, Washington University in St. Louis. 2013-present.

 

Patient Safety Officer, Department of Neurological Surgery, Washington University in St. Louis. 2011-present.

 

Search Committee for Chairman, Dept. of Orthopaedic Surgery, Washington University in St. Louis. 2013-2014.

 

Trauma/Neurosurgery Department Liaison. 2010-present. 

 

Tenured Professors Focus Group, University-wide Institute for the Study of Race, Washington University in St. Louis, 2016

 

Medical Licensure and Board Certification:

 

State Licensure              Missouri              2003017054              07/01/03-01/31/16 (Active)

 

              Illinois              036107966              10/04/02-07/31/17 (Active)

 

              Washington              025209 MD00036017              04/18/98-05/11/17 (Active)

 

Board Certification                Diplomate of the American Board of Neurological Surgery

              Exam completed and passed May 2010

 

 

Honors and Awards:

 

1988-1989   Stanford University-Krupp Foundation Research Fellow 1989

 

1991-1993   President Yale Medical School Class of 1994

 

1992-1993   Yale Medical School Jordan Scholar 1992 & 1993

 

1992            American Society For Bone and Mineral Research Young Investigator

                    Award

 

1993-1994   Howard Hughes-NIH Research Fellow 1993-1994

 

 

Editorial Responsibilities

             

              Section Editor – Spine, Youmans Neurological Surgery, 7th Edition.

 

 

Professional Societies and Organizations:

 

American Association of Neurological Surgeons – Active Member 2009-present. 

 

AO Spine – Active Member 2013-present.

 

Congress of Neurological Surgeons – Active Member 2004-present.

 

NFL – Unaffiliated Neuro Consultant. 2013-Present.

 

North American Spine Society- Active Member 2012-present.

 

St. Louis Spine Society – Founding Member, 2007-present. President 2008-2009.

 

 

Major Invited Professorships and Lectureships:

 

Courses and Invited Lectures

 

1.              “Minimally Invasive Spine Surgery” at Washington University School of Medicine Department of Neurology Grand Rounds.  St, Louis, MO. March 26, 2004.

 

2.              “Cervical Tumors and Infections: Surgical Considerations” at Complex Spine and Instrumentation.  Practical Anatomy Workshop. Faculty. St. Louis, MO,  April 2-4, 2004.

 

3.              “Positioning for Posterior Cervical Foraminotomy” at the 9th Advanced Techniques in Cervical Spine Decompression & Stabilization.  Practical Anatomy Workshop. Faculty. St. Louis, MO,  April 16-18, 2004.

 

4.              “Minimally Invasive Lumbar Procedures”  at Advances in Spinal Decompression and Fixation.  Practical Anatomy Workshop. Faculty. St. Louis, MO.  April 16-18, 2004.

 

5.              “Occipital Cervical Fusion: Practical Demonstration” at Advances in Spinal Decompression and Fixation.  Practical Anatomy Workshop. Faculty. St. Louis, MO.  April 16-18, 2004.

 

6.              Thoracic and Lumbar Stabilization and Fusion:  Indications and Complications at the 72nd AANS.  Faculty. Orlando, FL. May 1, 2004.

 

7.              Modern Techniques and Future Trends in Lumbar Interbody Fusion at the 72nd AANS Annual Meeting. Faculty. Orlando, FL. May 2, 2004.

 

8.              “Lumbar Interbody Fusion” at Team Approach to the Operative Management of the Spinal Surgery Patient, AO ASIF Spine Course for Operating Room Personnel. Overland Park, KS. July 17-18, 2004.

 

9.              Surgical Approaches to the Thoracic & Lumbar Spine at 73rd AANS Annual Mtg. Faculty. New Orleans, LA. April 17, 2005.

 

10.              “Spinal Decompression & Fixation”, Practical Anatomy Workshop. Faculty. St. Louis, MO.  March 13-14, 2005.

 

11.              “Approach Indications for Surgery and Medical Management of Back Pain. Krueger Symposium, Evansville, IN.  April 26-27, 2005.

 

12.              “Complex Spine: Anatomy & Instrumentation for Nurses and Physician Assistants.” 

Practical Anatomy Workshop. Faculty. St. Louis, MO. May 13-14, 2005.

 

13.              Stryker Oasys Post cervical system.  12th International meeting on Advanced Spine Techniques.  Presenter.   July 6-11, 2005. 

 

14.              “Positioning for Posterior Cervical Foraminotomy”.  Practical Anatomy Workshop.  Faculty.  St. Louis, MO  August 8-9, 2005.

 

15.              “Positioning for Posterior Cervical Foraminotomy”.  Practical Anatomy Workshop.  Faculty.  St. Louis, MO  January 10-11, 2006.

 

16.              “Cervical Tumors and Infections:  Surgical Considerations” at Complex Spine and Instrumentation.  Practical Anatomy Workshop.  Faculty.  St. Louis, MO. March 23-24, 2006.

 

17.              “Positioning for Posterior Cervical Foraminotomy” Practical Anatomy Workshop.  Faculty.  St. Louis, MO.  April 7-8, 2006.

 

18.              Thoracic and Lumbar stabilization and Fusion:  Indications and Complications at the 74th AANS.  Faculty.  San Francisco, CA.  April 22-25, 2006.

 

19.              “Positioning for Posterior Cervical Foraminotomy” Practical Anatomy Workshop.  Faculty.  St. Louis, MO.  May 6-7, 2006.

 

20.              13th Advanced Techniques in Cervical Spine Decompression and Stabilization.  Practical Anatomy Workshop.  Faculty.  St. Louis, MO.  September 8-10, 2006.

 

21.              Minimally Invasive:  Posterior Cervical Discectomy and Foraminotomy/Discectomy.  NASS.  Pre-meeting course.  Seattle, WA. October 1, 2006.

 

22.              “Positioning for Posterior Cervical Foraminotomy”.  Practical Anatomy Workshop.  Faculty.  St. Louis, MO May 18-19, 2007.

 

23.              14th Advanced Techniques in Cervical Decompression and Stabilization.” Practical Anatomy Workshop.  August 3-4, 2007.

 

24.              “Cervical Tumors and Infections:  Surgical Considerations” at Complex Spine and Instrumentation.  Practical Anatomy Workshop.  Faculty.  St. Louis, MO.  September 26, 2007.

 

25.              “Minimally Invasive:  Posterior Cervical Discectomy and Foraminotomy/Discectomy.”  NASS.  Pre-meeting course.  Austin, TX  October 22-24, 2007.

 

  1. 1st CRCS Cervical Spine Decompression and Stabilization Techniques, Practical Anatomy and Surgical Education, St. Louis, MO.  January 18-19, 2008.

 

  1. NASS Cervical Spine Stabilization, Chicago, 5/16-17, 2008

 

  1. 15th Advanced Techniques in Cervical Decompression and Stabilization.”  Practical Anatomy Workshop.  August 1-2, 2008.

 

  1. Complex Spine:  Anatomy and Instrumentation.  Practical Anatomy Workshop.  September 17-18, 2008.

 

  1. 2nd Annual Cervical Spine Decompression and Stabilization Techniques. Practical Anatomy and Surgical Education (PASE).  St. Louis, MO, January 30, 2009.

 

  1. “Minimal Access Management of Spinal Disease: Case Review with Experts.”  AANS Annual Meeting.  San Francisco, CA, May 3, 2009.

 

  1. Cervical Spine Decompression and Stabilization.  PASE.  St. Louis, MO, July 6, 2009.

 

  1. Complex Spine: Anatomy and Instrumentation.  PASE.  St. Louis, MO,                  September 16-17, 2009.

 

  1. Current and Emerging Issues in Lumbar Spine Surgery.  PASE.  St. Louis, MO,

October 15-18, 2009.

 

  1. 3rd Annual Cervical Spine Decompression and Stabilization Techniques.  PASE.  January 28-30, 2010.

 

  1. “Minimally Invasive Spinal Neurosurgery: Indications, Techniques, and Complications.” AANS Annual Meeting, Philadelphia, PA.  May 1-5, 2010.

 

  1. III Reunion Internacional de Neurocirugia Base de Craneo y Columna 2010.  Visiting Professor.  Santiago de Queretaro, Mexico.  June 2-5, 2010.

 

  1. American Association of Neurological Surgeons, Goodman Oral Board Preparation: Neurosurgery Review by Case Management Course.  Houston, Texas.  May 16-18, 2010.

 

  1. Practical Anatomy and Surgical Education.  The 17th Advanced Techniques in Cervical Spine Decompression and Stabilization.  St. Louis, MO.  August 5-7, 2010.

 

  1. Complex Spine:  Anatomy and Instrumentation.  Practical Anatomy Workshop.  September 15-16, 2010.

 

  1. PASE Cervical Course. St. Louis, MO.  July 9-11, 2012

 

  1. Hands on Cadaver Workshop for Spine Fellows. St. Louis, MO.  Nov 2-4, 2012.

 

  1. Complex Spine Anatomy and Instrumentation for Nurses and Pa’s. St. Louis, MO.  Sept 19-20, 2012.

 

  1. PASE Lumbar Course. St. Louis, MO. Nov 8-10, 2012.

 

  1. CSRS Cervical Course. St. Louis, MO. Feb 21-23, 2013.

 

  1. SNS Junior Resident Boot Camp: St. Louis, MO.  Jun 1, 2013.

 

  1. Cedars Sinai 13th Annual Current Concepts Spinal Disorders. Faculty.  Las Vegas, NV. Jan 30-Feb 2, 2014.

 

  1. BJH/WUSM Patient Safety and Quality Symposium.  Faculty.  St. Louis, MO.  Feb 21, 2014.

 

  1. One Spine Master’s Course. Faculty. Seattle, WA. June 27, 2014.

 

  1. Fifth Annual ONE Spine Residents & Fellows Course.  Faculty.  Seattle, WA. 

Aug 15-17, 2014.

 

  1. Innovative and Advanced Surgery of the Degenerative and Deformed Lumbar Spine.  Practical Anatomy and Surgical Education.  Faculty.  St. Louis, MO.  Oct 1-2, 3014.

 

  1. Complex Spine:  Anatomy & Instrumentation.  Practical Anatomy and Surgical Education.  Faculty.  St. Louis, MO.  Jan 14, 2015.

 

  1. Spinal Surgery LIVE.  Faculty.  Washington University School of Medicine, St. Louis, MO.  Feb 12, 2015. 

 

  1. Multidisciplinary Care of Spinal Tumors- Physician Outreach Presentation.  Anderson Hospital, Maryville, IL.  Mar 11, 2015.

 

  1. 8th Annual CSRS Cervical Spine Decompression & Stabilization Techniques.  Practical Anatomy and Surgical Education.  Faculty.  St. Louis, MO.  Apr 23-25, 2015.

 

  1. Innovative and Advanced Surgery of the Degenerative and Deformed Lumbar Spine.  Practical Anatomy and Surgical Education.  Faculty.  St. Louis, MO.  Aug 20-22, 2015.

 

  1. The 22nd Advanced Techniques in Cervical Spine Decompression & Stabilization. 

Faculty. Practical Anatomy and Surgical Education.  Faculty.  St. Louis, MO.  Sept 10-12, 2015. 

 

  1. 9th Annual CSRS Cervical Spine Decompression & Stabilization Techniques.  Practical Anatomy and Surgical Education.  Faculty.  St. Louis, MO.  Feb 18-20, 2016.

 

  1. SPINE MASTER’S Surgical Techniques; The Live, Interactive Surgery Course.  Washington University School of Medicine.  Faculty.  St. Louis, MO.  May 19-21, 2016. 

 

  1. Complex Spine: Anatomy & Instrumentation Cadaver Course for Nurses, Nurse Practitioners and Physician Assistants.  Practical Anatomy and Surgical Education. Faculty. St. Louis, MO. June 2-4, 2016.

 

  1. “Management of Metastatic Spine Disease: Operative Treatment.” 80th Annual WOA Meeting. Indian Wells, California, September 30, 2016.

 

  1. “New Technology.” Comprehensive Spine Care Conference. St. Louis, MO. October 14, 2016.

 

  1. SPINE MASTER’S Surgical Techniques; The Live, Interactive Surgery Course.  Washington University School of Medicine.  Faculty.  St. Louis, MO.  May 18-20, 2017

 

 

 

Industry Invited Lectures

 

  1. Program Committee Spine Across the Sea.  July 29-Aug 2, 2012. Kauai. Moderator, Introduction: Cervical Spine Deformity Seminar.

 

  1. Zimmer Spine.  Occipital, Cervical, and Thoracic Course.  Henderson, Nevada.  August 13-14, 2010.

 

  1. Zimmer Spine.  Advanced Techniques in Cervicothoracic Spine Surgery.  Faculty.  Tampa, FL.  Sept 19-20, 2014. 

 

  1. Ulrich Medical USA.  Advanced Techniques in Vertebral Body Replacement.  Faculty. Houston, TX.  April 24, 2015. 

 

  1. Zimmer Institute.  Advanced Techniques in Cervicothoracic Spine Surgery.  Faculty.  Tampa, FL.  May 15-16, 2015. 

 

 

 

Consulting Relationships and Board Memberships

 

Consulting Agreements              Aesculap Implant Systems

              Corelink, Inc.

              DePuy Spine             

Globus Medical

Gyrus ACMI, Inc.

Orthovita, Inc.

Osteotech, Inc.

              Salient Surgical Technologies, Inc.

Tissuelink Medical, Inc.

              Stryker Spine, Inc.

              Ulrich Medical

              Zimmer Spine, Inc.

 

Grants

 

NIH-NRSA: “Quantitative Analysis of Brain Tumor Invasion” 2000-2002

 

Patents

 

U.S. Patent No. 8,364,258 issued on January 29, 2013 (Docket #0307-004-023-C00001) and U.S. Patent No. 8,725,251 issued on May 13, 2014 (Docket #0307-004-023-C1C001), both entitled “Device, Method, and System for Neural Modulation as Vaccine Adjuvant in a Vertebrate Subject” assigned to the Invention Science Fund.

 

U.S. Patent No. 8,788,037 B2 issued on July 22, 2014. Device, Method, and System for Neural Modulation as Vaccine Adjuvant In A Vertebrate Subject. 

 

 

Research Experience

 

1/89-6/89:        Krupp Foundation/Stanford University Research Fellow at the German Primate Centre, Göttingen, FRG in the Department of Virology and Immunology under the supervision of Dr. Gerhard Hunsmann, M.D.  Worked on the seroprevalence of HIV-1,-2 and HTLV-I antibodies in samples from Nigerian STD clinics and South American Indians and the culture of HIV-1 and HTLV-II for this purpose.

 

10/89-5/90:      Undergraduate honors thesis in the laboratory of Dr. Steven Foung, M.D., Stanford University Blood Bank.  "The Development of Serological Techniques for the Differential Diagnosis of Human T-cell Leukemia Virus Types I and II."

 

6/90-8/90:        Research Assistant at the Stanford University Blood Bank in the laboratory of Dr. Steven Foung, M.D.  Worked on the use of HTLV-I and HTLV-II recombinant peptides in the diagnosis of HTLV infection in American and Japanese blood donors.

 

6/91-5/95:        M.D. thesis work in the laboratory of Dr. Roland Baron, D.D.S., Ph.D., Departments of Cell Biology and Orthopaedics and Rehabilitation, Yale University School of Medicine on the mechanisms of osteoclast activation in mice transgenic for the transactivating gene (tax) of HTLV-I.

 

10/93-8/94:      Howard Hughes-NIH Research Scholar in the laboratory of Dr. Stefan Karlsson, M.D., Ph.D., Medical Molecular Genetics Section, Developmental and Metabolic Neurobiology Branch, National Institutes of Neurologic Disorders and Stroke, National Institute of Health.   Worked on the development of a murine embryonic stem cell line lacking both copies of the transforming growth factor-ß1 (TGF-ß1) gene for use as an in vitro model of early embryonic development and differentiation.

 

1/98-8/02:  Research in the laboratory of Dr. Daniel Silbergeld in the Department of Neurological Surgery at the University of Washington.  Supported by the University of Washington Department of Neurological Surgery training grant.  Working on in vivo and in vitro models of glial tumor migration in humans and rats.  Additional projects include studying differences in tumor responsiveness to different chemotherapeutic agents/radiation and the development of high frequency utltrasound as a clinical tool.

 

 

Clinical Trials

 

A Prospective, Multi-Center, Randomized Controlled Study to Compare the Spinal Sealant System as an Adjunct to Sutured Dural Repair with Standard of Care Methods during Spinal Surgery.  Protocol Number: DRS-05-001

A Prospective, Multi-Center, Randomized Controlled Study to Compare the Spinal Sealant System as an Adjunct to Sutured Dural Repair to Standard of Care Methods during Spinal Surgery.  Protocol Number DS3-06-002

Intervertebral Disc for the Treatment of Radicular Symptoms Associated with Degenerative Disc Disease (DDD), Disc/Osteophyte Complex or Herniated Disc of the Cervical Spine.

 

Pilot Study of Clinical Safety and Feasibility of the PLGA Poly-L-Lysine Scaffold for

the Treatment of Complete (AIS A) Traumatic Acute Spinal Cord Injury.

 

  

Publications—Journal Articles

 

1.              Lipka JJ, Santiago P, Chan L, Reyes GR, Samuel KP, Blattner WA, Shaw GM, Hanson CV, Sninsky JJ, Foung SK.  Modified western blot assay for confirmation and differentiation of human T-cell lymphotropic virus types I and II.  J. Infect Dis. 1991 Aug; 164(2):400-3.

 

2.              Inoue D, Santiago P, Horne WC, Baron R.  Identification of an osteoclast transcription factor that binds to the human T-cell leukemia virus type I-long terminal repeat enhancer element.  J Biol Chem.1997 Oct 3;272(40):25386-93.

 

3.              Schuster JM, Santiago P, Elliott JP, Grady MS, Newell DW, Winn HR. Acute traumatic posteroinferior cerebellar artery aneurysms: report of three cases.  Neurosurgery, 1999 Dec;45(6):1465-7;discussion 1467-8.

 

4.              Fukuhara T, McKhann GM 2nd, Santiago P, Eskridge JM, Loeser JD, Winn HR. Resolution of central pain after embolization of an arteriovenous malformation. Case report.  J Neurosurg, 1999 Mar;90(3):575-9.

 

5.              Mourad P, Farrell L, Stamps LD, Santiago P, Fillmore HL, Broaddus WC, Silbergeld DL. Quantitative assessment of glioblastoma invasion in vivo. Cancer Lett.  2003 Mar 20;192(1):97-107.

 

6.              Mesiwala AH, Farrell L, Santiago P, Ghatan S, Silbergeld DL: The effects of hydrogen peroxide on brain and brain tumors.  Surg Neurol, 2003 May;59(5):398-407;discussion 407.

 

7.              Sandhu FA, Santiago P, Fessler RG, Palmer S.  Minimally invasive surgical treatment of synovial cysts.  Neurosurgery. 2004 Jan;54(1):107-11;discussion 111-2.

 

8.              Mohit AA, Santiago P, Rostomily R. Intramedullary tuberculoma mimicking primary CNS lymphoma. J Neurol Neurosurg Psychiatry. 2004 Nov;75(11):1636-8.

 

9.              Isaacs RE, Podichetty VK, Sandhu FA, Santiago P, Spears JD, Aaronson O, Kelly K, Hrubes M, Fessler RG: Thoracic microendoscopic discectomy: a human cadaver study.  Spine. 2005 May 15;30(10):1226-31.

 

10.              Isaacs RE, Podichetty VK, Santiago P, Sandhu FA, Spears J, Kelly K, Rice L, Fessler RG.  Minimally invasive microendoscopy-assisted transforaminal lumbar interbody fusion with instrumentation.  J Neurosurg Spine. 2005 Aug;3(2):98-105.

 

11.              Tredway TL, Santiago P, Hrubes MR, Song JK, Christie SD, Fessler RG.  Minimally invasive resection of intradural-extramedullary spinal neoplasms.  Neurosurgery 2006 Feb;58(1 Suppl):ONS52-8; discussion ONS52-8.

 

12,              Ashley WW Jr, Rivet D, Cross DT 3rd, Santiago P. Development of a giant vertebral artery pseudoaneurysm following a C1 fracture: case illustration.  Surg Neurol. 2006 Jul;66(1):80-1

 

13.              Santiago P, Fessler RG.  Minimally invasive surgery for the management of cervical spondylosis.  Neurosurgery 2007 Jan;60(1 Suppl 1):S160-5.

 

14.              Rosen DS, Tredway TL, Santiago P and Fessler RG:  Minimally Invasive Resection of a Spinal Epidural Cavernous HemangiomaJapanese Journal of Spine Surgery.  In press 2005.

 

15. Limbrick DD Jr, Behdad A, Derdeyn CP, Custer PL, Zipfel GJ, Santiago P Traumatic enucleation with avulsion of the ophthalmic artery resulting in aneurysm-like subarachnoid hemorrhage. J Neurosurg 2009 Oct;111(4):653-7.

 

16. Refai D, Dunn GP, Santiago PGiant cell tumor of the thoracic spine: case report and review of the literature. Surg Neurol. 2009 Feb;71(2):228-33; discussion 233, Epub 2008 Jan 22.

 

17. Kasukurthi R, Ray WZ, Lusis EA, Santiago P. Intramedullary capillary hemangioma of the thoracic spine: Case report and review of the literature.  Rare tumors. 2009; Epub 1:e10.

 

18.  Chicoine MR, Lim CC, Evans JA, Singla A, Zipfel GJ, Rich KM, Dowling JL, Leonard JR, Smyth MD, Santiago P, Leuthardt EC, Limbrick DD, Dacey RG.  Implementation and preliminary clinical experience with the use of ceiling mounted mobile high field intraoperative magnetic resonance imaging between two operating rooms.  Acta Neurochir Suppl:  2011; 109:97-102.

 

19. Hawasli AH, Buckley RT, Gao F, Limbrick DD, Smyth MD, Leonard JR, Santiago P, Stewart TJ, Park TS, Grubb RL, Dowling JL, Leuthardt EC, Rich KM, Zipfel GJ, Dacey RG, Chicoine MR.  Neurosurgery. 2013 Apr 29.

 

20.  Are readmission rates on a neurological service indicators of quality care? Shah MN, Stoev IT, Sanford DE, Gao F, Santiago P, Jacques DP, Dacey RG Jr. J Neurosurg. 2013 Apr 26.

 

21.  Bumpass DB, Buchowski JM, Park A, Gray BL, Agarwal R, Baty J, Zebala LP, Riew KD, Santiago P, Ray WZ, Wright NM.  An update on civilian spinal gunshot wounds; treatment, neurological recovery, and complication.  Spine (Phila Pa 1976).  2015 Apr 1:40 (7); 450-61.

 

22.  Sun SQ, Cai C, Ravindra VM, Gamble P, Yarbrough CK, Dacey RG, Dowling JL, Zipfel GJ,

Wright NM, Santiago P, Robinson CG, Schmidt MH, Kim AH, Ray WZ.  Simpson Grade I-III resection of spinal atypical (World Health Organization Grade II) meningiomas is associated with symptom resolution and low recurrence. Neurosurgery. 2015 Jun; 76(6):739-46.

 

      23.  Murphy R, Pen S, Xu J, Wang Y, Sullivan S, Gamble P, Wagner J, Wright N, Dorward I, Riew

            D, Santiago P, Kelly M, Trinkaus K, Ray W, Song S.  Magnetic resonance imaging biomarker of

             axon loss reflects cervical spondylotic myelopathy severity.  SPINE-S-15-00662 –2015.

            (Submitted article).

 

24. Murphy RK, Sun P, Han RH, Griffin KJ, Wagner JM, Yarbrough CK, Wright NM, Dorward IG, Riew D, Kelly, MP, Santiago P, Zebala LP, Trinkaus K, Ray WZ, Song SK.   Fractional anisotropy to quantify cervical spondylotic myelopathy severity.  J Neurosurg Sci. 2016 May 5. (Epub ahead of print). PMID: 27149369 (PubMed – as supplied by publisher).

 

 

25.  Zenga J, Sharon JD, Santiago P, Nussenbaum B, Haughey BH, Fox IK, Myckatyn TM, Diaz JA,

Chicoine MR.  Lower trapezius flap for reconstruction of posterior scalp and neck defects after

complex occipital-cervical surgeries.  J Neurol Surg B Skull Base.  2015 Sep; (76(5):397-408.

Doi.1055/s-0034-1544123. Epub 2015 May 22. PMID: 26401483. (PubMed).

 

26. Sun SQ, Cai C, Ravindra VM, Gamble P, Yarbrough CK, Dacey RG, Dowling JL, Zipfel GJ, Wright NM, Santiago P, Robinson CG, Schmidt MH, Kim AH, Ray WZ. Simpson grade I-III resection of spinal atypical (World Health Organization Grade II) meningiomas is associated with symptom resolution and low recurrence.  Neurosurgery. 2015 Jun; 76(6):739-46. Doi: 10.1227/NEU.0000000000000720. PMID: 25774702 (PubMed-indexed for MEDLINE).

 

27. Madaelil TP, Long JR, Wallace AN, Baker JC, Ray WZ, Santiago P, Buchowski J, Zebala LP, Jennings JW. Preoperative fiducial marker placement in the thoracic spine: A technical report. Spine (Phila Pa 1976).  2017 May 15;42 (10): E624-E628.

                                          

 

Abstracts

 

1.              Hadlock KG, Lipka JJ, Santiago P, Bui KL, Moeckli R, et al.  Cloning and analysis of an HTLV-II specific recombinant antigen from the envelope region of HTLV-II.  Abstract. 4th International Conference on Human Retrovirology: HTLV, Montego Bay, Jamaica, 1991.

 

2.              Santiago P, Horne WC, Neff L, Horowitz M, Li CB, Ruddle NH, Baron R.  Osteoclast restricted and 1,25 (OH) 2 Vitamin D3 dependent expression of the tax gene product in HTLV-I tax transgenic mice.  Abstract. 14th Annual Meeting of the American Society for Bone and Mineral Research, Minneapolis, 1992.

 

3.              Santiago P, Kulkarni A, Yaswen L, Karlsson S.  Development of a TGF-ß1 double knockout embryonic stem cell line for use as an in vitro model of early development and differentiation.  Presented at the 10th Annual International Medical Student Congress, Istanbul, Turkey, 1994.

 

4.              Santiago P, Ojemann G, Silbergeld D.  Surgical disruption of the arcuate fasciculus does not result in aphasias.  Abstract.  Annual Meeting American Epilepsy Society, San Diego, 1998.

 

5.              Mourad P, Mesiwala A, Farrell L, Sokolov D, Vaezy S, Santiago P, Mayberg MR, Crum L, Silbergeld DL: Ultrasound opens the blood brain barrier without damage in vivo. Abstract, IEEE International Ultrasonics Symposium, 1999.

 

6.              Santiago P, Farrell L, Silbergeld D: Chemosensitivity profiles of glioblastoma cell lines derived from gross tumor and from invading cells. Abstract. Annual Meeting of the American Association of Neurological Surgeons, New Orleans, 1999

 

7.              Santiago P, Spence AM, Silbergeld D. Stelzer KJ: Re-resection and low activity I-125 brachytherapy for recurrent glioblastoma. Abstract. American Association of Neurological Surgeons, New Orleans, 1999

 

8.              Lipka JJ, Santiago P, Chan L, Reyes GR, Hanson CV, Blattner WA, Foung SKH.  One step serological confirmation and typing of HTLV-I/II infection.  Abstract. Annual Meeting of the American Association of Neurological Surgeons, New Orleans, 1999

 

9.              Mesiwala A, Santiago P, Ghatan S, Farrell L, Silbergeld D: Affects of hydrogen peroxide on human and rat brain and brain tumors. Abstract, Society for Neuro-Oncology, 2000.

 

10.              Santiago P, Farrell L, Silbergeld D:  In Vitro evaluation of ethanol and peroxide for resection cavity application following pituitary microadenoma resection. Abstract. Annual Meeting of the American Association of Neurological Surgeons, San Francisco, 2000.

 

11.              Sandhu FA, Santiago P, Palmer S, Fessler RG: Minimally invasive surgical treatment of lumbar synovial cysts.  Abstract.  Annual Meeting of the Congress of Neurological Surgery.  Denver, 2003.

 

12.              Santiago P, Sandhu FA, Fessler RG: Microendoscopic technique for the management of cervical spinal canal stenosis.  Abstract. Annual Meeting of the Congress of Neurological Surgery.  Denver, 2003.

 

13.              Perez-Cruet MJ, Sandhu FA, Santiago P, Issacs RE, Fessler RG: Minimally invasive microendoscopic thoracic discectomy.  Abstract. Annual Meeting of the American Association of Neurological Surgeons, San Diego, 2003.

 

14.              Isaacs R, Aaronssen O, Santiago P, Sandhu F, Fessler, RG: Percutaneous thoracic pedicel screw placement. Abstract. Annual Meeting of the American Association of Neurological Surgeons, San Diego, 2003.

 

15.              Issacs RE, Aaronssen O, Sandhu FA, Santiago P, Fessler, RG: Thoracic microendoscopic discectomy.  Abstract. Annual Meeting of the American Association of Neurological Surgeons, San Diego, 2003.

 

16.              Perez-Cruet MJ, Santiago P, Sandhu FA, Foley KT, Fessler RG:  Accuracy and safety of percutaneous pedicle screw placement for degenerative lumbar disease.  Abstract. Annual Meeting of the American Association of Neurological Surgeons, San Diego, 2003.

 

17.              Trent L. Tredway,MD, Paul Santiago, MD, Bong-Soo Kim,MD, Laurie Rice, RN NP, and Richard G. Fessler, MD, PhD. Removal of far lateral herniated discs via a minimally-invasive technique. Abstract.  Annual Meeting Joint Section AANS/CNS on Spinal Disorders and Peripheral Nerve, San Diego, 2004.

 

18.              Trent L. Tredway,MD, Paul Santiago, MD, Bong-Soo Kim, MD, Max Lee, MD, and Richard G. Kessler, MD, PhD. Resection of spinal intradural neoplasms via a minimally-invasive technique. Abstract.   Annual Meeting Joint Section AANS/CNS on Spinal Disorders and Peripheral Nerve, San Diego, 2004.

 

19.              Trent L. Tredway, MD, Paul Santiago, M.D., Bong-Soo Kim, M.D., Laurie Rice, RN, NP and Richard G. Fessler, M.D., Ph.D.  Two level minimally-invasive transforaminal lumbar interbody fusion (MI-TLIF) with three arm SextantTM instrumentation. Abstract. Annual Meeting Joint Section AANS/CNS on Spinal Disorders and Peripheral Nerve, San Diego, 2004.

 

20.  Scientific Program Committee/Abstract Reviewer NASS 2013.

 

 

Resident and Medical Student Lectures

 

1.              “Low Back Pain” at Lunch and Learn (Washington University Neurology Teaching Conference).  St. Louis, MO.  June 8, 2004.

 

2.              “Methylprednisolone/Acute Spinal Cord Injury” (Neurosurgery Residents’ Dinner Journal Club). St. Louis, MO June 9, 2004.

 

3.              “Low Back Pain” Washington University School of Medicine. August 2004.

 

4.              “Cervical Spine and Low Back Pain”.  Washington University School of Medicine, Third Year Medical Students.  February 1, 2007.

 

  1. Resident Spine Cadaver Course.  Washington University School of Medicine, 2013-   Present.

 

  1. Diagnosis and management of intradural (intramedullary and extramedullary) spinal tumors, benign and malignant.  Washington University School of Medicine, Ortho/Spine Fellow Core Curriculum Lecture. June 29, 2015. 

 

  1. Diagnosis and management of intradural (intramedullary and extramedullary) spinal tumors, benign and malignant.  Washington University School of Medicine, Ortho/Spine Fellow Core Curriculum Lecture. May 15, 2017. 

 

 

Book Chapters

 

1.              Santiago, P, Silbergeld D: Pharmacology and Utility of Common Neurosurgical Drugs, in Textbook of Neurological Surgery, 2nd Edition, Lipincott Williams and Wilkins, 2002.

 

2.              Santiago P, Fine AD, Shafron D, Fessler RG: Benign Extradural Lesions of the Dorsal Spine in Youman’s Neurological Surgery, Fourth Edition, WB Saunders Co., Philadelphia, 2003.

 

3.              Santiago P, Fessler RG: Trauma Surgery Fractures of the Lumbar and Sacral Spine in Spine Surgery: Techniques, Complication Avoidance and Management, Churchill Livingstone, Philadelphia, 2003. 

 

4.              Santiago P, Fessler RG: Lumbar microendoscopic Laminoforaminotomy and Discectomy in Endoscopic Spinal Surgery, Thieme, New York, 2003.  Submitted for publication.

 

5.              Santiago P, Fessler RG: Trauma of the Nervous System in Neurology in Clinical Practice, Fourth Edition, Elsevier Publishing, Co., St, Louis, 2003. 

 

6.              Santiago P, Silbergeld D:  Malignant Gliomas in Youman’s Neurological Surgery, Fourth Edition, WB Saunders Co., Philadelphia, 2003.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

August 2017

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